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AIDS cure discovered?
#1
For the first time, researchers succeded in removing the HIV virus from cells under laboratory conditions.
http://www.dw-world.de/dw/article/0,2144...28,00.html
Quote:German scientists have succeeded in snipping the virus that causes AIDS out of human cells, leaving them healthy again. The procedure is a breakthrough in bio-technology and fuels hope of a cure for AIDS.

The laboratory procedure removing the AIDS virus used an enzyme, said Joachim Hauber of the Heinrich Pette Institute for Experimental Virology and Immunology in Hamburg.

"We have rid the cells of the virus," Hauber said on Thursday. "No one else has done this before." He called it "a breakthrough in bio-technology."

Hauber said it was his "cautious" hope that a cure for AIDS could be found within 10 years.

Current therapies can only limit the spread of the human immunodeficiency virus (HIV) and not remove it from the body. HIV is a retrovirus that nests in the DNA or key genetic material of infected cells.

The Max Planck Institute for Molecular Cell Biology and Genetics in Dresden was the partner in the research, which will be reported in Friday's issue of the scientific journal Science.

Three years of experiments on mice were planned next, to be followed by tests on humans in Hamburg.

Bildunterschrift: Großansicht des Bildes mit der Bildunterschrift: The enzyme knows just where to cut the DNA
The scientists' method used the ability of so-called recombinase enzymes to cut strands of DNA at certain places like a pair of scissors and recombine the strands.

The new enzyme, Tre, always recognized the right spot to snip the DNA where the HIV started. The scientists said it recognized a characteristic HIV sequence that scarcely ever mutated.

Tre was adapted from an existing natural enzyme, Cre, which recognized similar genetic sequences.

Stem cells necessary for therapy

The laboratories artificially evolved Cre into Tre through more than 120 recombinase generations. Hauber said the cell then flushed out the snipped-away DNA as waste.

Any therapy, though, would require stem cells to be obtained from a patient's blood. They would then be treated in the laboratory and re-injected to regenerate a healthy immune system, Hauber said.

"It's high-tech medicine," Hauber said. "You couldn't just take a pill."
"You know, Paul, Reagan proved that deficits don't matter." Dick Cheney
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#2
Just for clarity, the article said
Quote:Any therapy, though, would require stem cells to be obtained from a patient's blood. They would then be treated in the laboratory and re-injected to regenerate a healthy immune system, Hauber said.
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#3
Yes, it's odd. Why do they cannibalise embryos what's an ethical problem, if they can obtain them from the person who needs the treatment?
"You know, Paul, Reagan proved that deficits don't matter." Dick Cheney
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#4
quadrat Wrote:Yes, it's odd. Why do they cannibalise embryos what's an ethical problem, if they can obtain them from the person who needs the treatment?

That is an easy one. There is another motive involved, and that is abortion. The Pro abortion crowd will do anything to keep from having abortions restricted, thus the kooky contortions they go to in order to ensure funding/open clinics/ease of access, to have unlimited abortions. And since fetal stem cell come mostly from "take a wild guess", they want these to be the cells of choice.

Follow the money and ideology.
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“Socialism always begins with a universal vision for the brotherhood of man and ends with people having to eat their own pets.”
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#5
Can't tell. I'm pro-abortions, but against using stem cells in general, and particularly from embryos. Abortion is personal freedom, but embrionic stem cell use an unethical business, that's why. I don't think the former mothers are asked whether they agree to cannibalise the embryos, and if they will in future, some abortions could occur for the money involved. I don't think either it's good to harvest cells from living embryos, no matter how much the doctors assure you it's safe.
"You know, Paul, Reagan proved that deficits don't matter." Dick Cheney
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